233. Anders Corbett: On “Crafting” Your Gut Microbiome, Probiotics, Leaky Gut & Hormone Optimization - The Ultimate Human with Gary Brecka Recap

Podcast: The Ultimate Human with Gary Brecka

Published: 2026-01-09

Duration: 1 hr 27 min

Guests: Anders Corbett

Summary

Anders Corbett, CEO of Craft Microbiome, discusses how the gut microbiome can be cultivated to enhance health and athletic performance. He also highlights the potential of banking young bacteria to mitigate age-related decline and neurodegenerative diseases.

What Happened

Anders Corbett, CEO of Craft Microbiome, delves into the significance of the gut microbiome in maintaining youth and health. He explains how a woman who lived to 118 had a microbiome akin to a 35-year-old's, signaling the potential for longevity linked to gut health.

Corbett discusses how specific bacterial strains in the gut are associated with athletic performance. For example, cyanobacteria found in Olympic swimmers suggest a link between microbiome composition and physical prowess. He also notes that some probiotics can lead to significant muscle gains, as evidenced by an individual who gained 25 pounds of muscle in a month.

The conversation touches on the role of the gut microbiome in preventing neurodegenerative diseases. Corbett asserts that changes in the gut can predict conditions like Parkinson's years before symptoms appear, implying that genetic predispositions may not be as deterministic as once thought.

The potential of the gut microbiome to produce neurotransmitters and influence mood and behavior is also explored. Corbett highlights how serotonin and dopamine production in the gut can affect overall mental health.

Gary Brecka and Corbett discuss the importance of maintaining a healthy gut barrier to prevent conditions like leaky gut, which can lead to inflammation and immune issues. They emphasize the role of probiotics in restoring gut health after antibiotic use.

Corbett shares insights on improving gut health by banking young bacteria to reintroduce beneficial strains as one ages. This approach aims to sustain a youthful microbiome, potentially extending healthspan and reducing disease risk.

The episode concludes with a discussion on how Craft Microbiome plans to develop an app that suggests specific probiotics based on daily activities, offering personalized recommendations to optimize health.

Key Insights

• The gut microbiome of a woman who lived to 118 was similar to that of a 35-year-old, suggesting a strong link between gut health and longevity.
• Certain bacterial strains in the gut, such as cyanobacteria found in Olympic swimmers, are associated with enhanced athletic performance and physical capabilities.
• Changes in the gut microbiome can predict neurodegenerative diseases like Parkinson's years before symptoms manifest, indicating that genetic predispositions may not be as deterministic as traditionally thought.
• The gut microbiome can produce neurotransmitters like serotonin and dopamine, which play a significant role in influencing mood and overall mental health.